Liquid Chromatographic Determination of 6-, 8-, 10-Gingerol, and 6-Shogaol in Ginger (Zingiber officinale) as the Raw Herb and Dried Aqueous Extract
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چکیده
منابع مشابه
Optimization of Extraction Conditions for the 6-Shogaol-rich Extract from Ginger (Zingiber officinale Roscoe)
6-Shogaol, a dehydrated form of 6-gingerol, is a minor component in ginger (Zingiber officinale Roscoe) and has recently been reported to have more potent bioactivity than 6-gingerol. Based on the thermal instability of gingerols (their dehydration to corresponding shogaols at high temperature), we aimed to develop an optimal process to maximize the 6-shogaol content during ginger extraction by...
متن کاملPharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects.
BACKGROUND Ginger shows promising anticancer properties. No research has examined the pharmacokinetics of the ginger constituents 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol in humans. We conducted a clinical trial with 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol, examining the pharmacokinetics and tolerability of these analytes and their conjugate metabolites. METHODS Human vol...
متن کاملQuantification of 6-gingerol in Zingiber officinale extract, ginger-containing dietary supplements, teas and commercial creams by validated HPTLC densitometry
A sensitive and accurate high-performance thin layer chromatography (HPTLC) method has been developed to determine the quantity of 6-gingerol in the methanolic extract of Zingiber officinale containing dietary supplements, teas and commercial creams. 6-gingerol was separated on aluminumbacked silica gel 60 F254 plates with n-hexane:ethyl acetate 40:60 (%, v/v) as mobile phase. A compact band wa...
متن کاملHigh Performance thin layer Chromatographic Analysis of 10-Gingerol in Zingiber officinale Extract and Ginger-Containing Dietary Supplements, Teas and Commercial Creams
Ginger rhizome powder is widely used as a food spice and an herbal medicine around the world. A sensitive and accurate High Performance thin layer chromatographic (HPTLC) method has been developed to determine the quantity of 10-gingerol in Zingiber officinale extract and ginger-containing dietary supplements, teas and commercial creams on aluminum-backed silica gel 60 F254 plates with n-hexane...
متن کاملOptimization protocol for the extraction of 6-gingerol and 6-shogaol from Zingiber officinale var. rubrum Theilade and improving antioxidant and anticancer activity using response surface methodology
BACKGROUND Analysis and extraction of plant matrices are important processes for the development, modernization, and quality control of herbal formulations. Response surface methodology is a collection of statistical and mathematical techniques that are used to optimize the range of variables in various experimental processes to reduce the number of experimental runs, cost , and time, compared ...
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ژورنال
عنوان ژورنال: Journal of AOAC INTERNATIONAL
سال: 2007
ISSN: 1060-3271,1944-7922
DOI: 10.1093/jaoac/90.5.1219